Have the same problem with all three of my characters, all main story progression has disappeared from the starmap and notifications, and assignments no longer complete, resulting in the screen loading back in with no character and fixed camera in place of where character exited the map.

Had no problems prior to this so can only assume this has been caused by the most recent patch. Especially as it has affected all three characters simultaneously with each at different points in the campaign: crusader season 2 missions, assassin season 1 missions, and psyker main missions chapter 3.

hopefully it's a quick/easy fix if I have to start all three characters again then I'm done. Especially crusader lvl 74 all relic gear :( took a long time getting the gear for that build.

Was stuck on chapter 2 then deleted character now I can’t get past chapter 1.

I can't do anything after chapter 1

This just happened to me, chapter 4 clue 4 out of 7 follow the trail of drakan. I just posted with a screenshot right above you