I have the same problem. Startet several days ago, game was running perfectly before. Freezes always start, when I kill specific enemies (plague marines f.e.) or opening chests. Can even freez, when I'm defeating larger groups of enemies. But just the picture freezes for several second, in the backround I can hear ongoing music an battle sound. I can also hear, that I can move or shoot furthermore. I don't know, why this startet. Doesn't matter the grafic settings, if high or low. Grafic driver are actual.

I’m experiencing the same issue. Mine tends to do it mid mission. Kinda bummed because there was a lot of relic drops when it did it last time. Had to restart the game. I’m on PS5 with the Ultimate Edition.