Let me start off by saying, I'm stoked for this game. The potential is has is really amazing. Since it's Alpha, I'm not expecting polish at all. Let me start off with specs on my machine.
Windows 10 64 Bit
I5 4670K, Overclocked to 4.4 stable, 32 Gig 2400 Mhz ram, 970 GTX 4gig card. Running SSD drives
Game loads very quickly at this time.
Attempts to talk to vendor leads to crashing almost immediately.
Crashes so far cause loss of EQUIPPED items but not inventory.
FPS drops all over the place regardless of chosen settings, 25-30FPS is normal during firefights graphics slowdown is very rampant.
These are just some of the issues I've encountered, hopefully they can assist in some way.