I'll start by saying I'm a usability expert and that's a big part of what I do in my profession. Basically, how do people interact with apps, games, and devices.
There are two pretty big issues I've found from a usability standpoint that I think detract from the game.
- I can't understand a word that anyone is saying while someone is speaking to me while on a mission. It's all garbled and impossible to understand. I could read the text, but i'm not going to do that while fighting. What usually ends up happening is I miss the story content. Solution: Remove 90% of the sound effects on the audio file. You can still keep some of the grittiness from the audio, but at least make it easy to understand.
- The crafting interface is not intuitive at all. I had to watch a video on the internet on how to use the advanced materials. Solution: Make the glow effect impossible to miss when selecting a component.
These are just my thoughts anyway.