I’m experiencing the same issue. Mine tends to do it mid mission. Kinda bummed because there was a lot of relic drops when it did it last time. Had to restart the game. I’m on PS5 with the Ultimate Edition.

I have the same problem. Startet several days ago, game was running perfectly before. Freezes always start, when I kill specific enemies (plague marines f.e.) or opening chests. Can even freez, when I'm defeating larger groups of enemies. But just the picture freezes for several second, in the backround I can hear ongoing music an battle sound. I can also hear, that I can move or shoot furthermore. I don't know, why this startet. Doesn't matter the grafic settings, if high or low. Grafic driver are actual.